IGF1R (phospho Y1165/1166) polyclonal antibody
产品名称： IGF1R (phospho Y1165/1166) polyclonal antibody
英文名称： IGF1R (phospho Y1165/1166) polyclonal antibody
产品编号： PAB5727
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of IGF1R.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding Y1165/Y1166 of human IGF1R.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Mitogenicity and transforming activity of the insulin-like growth factor-I receptor with mutations in the tyrosine kinase domain.
Li S, Ferber A, Miura M, Baserga R.J Biol Chem. 1994 Dec 23;269(51):32558-64.
- Entrez GeneID:
- 3480
- Gene Name:
- IGF1R
- Gene Alias:
- CD221,IGFIR,JTK13,MGC142170,MGC142172,MGC18216
- Gene Description:
- insulin-like growth factor 1 receptor
- Omim ID:
- 147370
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq
- Other Designations:
- soluble IGF1R variant 1,soluble IGF1R variant 2
- Related Disease
- Abortion, Spontaneous
- Adenocarcinoma
- Adenoma
- Alzheimer Disease
- Alzheimer disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Aneuploidy
- Atherosclerosis
- Bacteremia
- Barrett Esophagus
- Birth Weight
- Body Weight
- Bone Diseases
- Brain Ischemia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Hepatocellular